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Term Information

Accession
GO:0032933
Name
SREBP signaling pathway
Ontology
biological_process
Synonyms
ER to nucleus sterol response pathway, ER-nuclear sterol response pathway, SREBP signalling, SREBP target gene transcriptional activation, SREBP-mediated signalling pathway, endoplasmic reticulum to nucleus sterol response pathway, endoplasmic reticulum-nuclear sterol response pathway, positive regulation of sterol regulatory element binding protein target gene transcription, positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response, sterol depletion response, SREBP target gene transcriptional activation, sterol response element binding protein signaling pathway, up regulation of sterol regulatory element binding protein target gene transcription, up-regulation of sterol regulatory element binding protein target gene transcription, upregulation of sterol regulatory element binding protein target gene transcription, SREBP-mediated signaling pathway, activation of sterol regulatory element binding protein target gene transcription, positive regulation of transcription via sterol regulatory element binding, positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway, stimulation of sterol regulatory element binding protein target gene transcription, sterol regulatory element binding protein target gene transcriptional activation
Alternate IDs
GO:0035104, GO:0006994, GO:0030967
Definition
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription. Source: GOC:signaling, PMID:22017871, PMID:12923525, GOC:vw, GOC:bf, GOC:mah
Comment
None
History
See term history for GO:0032933 at QuickGO
Subset
None
Feedback
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Graph of GO:0032933

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Parents of SREBP signaling pathway (GO:0032933)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
SREBP signaling pathway [is_a relation] is_a  positive regulation of transcription by RNA polymerase II (GO:0045944)
SREBP signaling pathway [is_a relation] is_a  ER-nucleus signaling pathway (GO:0006984)
SREBP signaling pathway [is_a relation] is_a  cellular response to sterol depletion (GO:0071501)
Children of SREBP signaling pathway (GO:0032933)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of SREBP signaling pathway (GO:2000640) [RO:0002213 relation] RO:0002213  SREBP signaling pathway
regulation of SREBP signaling pathway (GO:2000638) [RO:0002211 relation] RO:0002211  SREBP signaling pathway
sterol regulatory element binding protein cleavage (GO:0035103) [BFO:0000050 relation] BFO:0000050  SREBP signaling pathway
negative regulation of SREBP signaling pathway (GO:2000639) [RO:0002212 relation] RO:0002212  SREBP signaling pathway
None.