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Term Information

Accession
GO:0032783
Name
super elongation complex
Ontology
cellular_component
Synonyms
ELL-EAF complex, ELL-EAF-EBP complex
Alternate IDs
None
Definition
A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae. Source: PMID:30102332, PMID:17150956
Comment
None
History
See term history for GO:0032783 at QuickGO
Subset
None
Feedback
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Parents of super elongation complex (GO:0032783)
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super elongation complex [is_a relation] is_a  transcription elongation factor complex (GO:0008023)

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