negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

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• GO:0008150 biological_process
• GO:0042592 homeostatic process
•      GO:0019725 cellular homeostasis
•      GO:0048878 chemical homeostasis
•      BFO:0000001 entity
•      BFO:0000003 occurrent
•          GO:0015267 channel activity
•          GO:0055082 intracellular chemical homeostasis
•          GO:0051179 localization
•          GO:0050801 monoatomic ion homeostasis
•              GO:0065007 biological regulation
•              GO:0007154 cell communication
•              GO:0009987 cellular process
•              GO:0005575 cellular_component
•              GO:0051234 establishment of localization
•              GO:0022836 gated channel activity
•              GO:0098771 inorganic ion homeostasis
•              GO:0006873 intracellular monoatomic ion homeostasis
•              GO:0030001 metal ion transport
•              GO:0003674 molecular_function
•              GO:0055080 monoatomic cation homeostasis
•              GO:0005216 monoatomic ion channel activity
•              GO:0006811 monoatomic ion transport
•              BFO:0000015 process
•              GO:0050789 regulation of biological process
•              GO:0050794 regulation of cellular process
•              GO:0032879 regulation of localization
•              GO:0043269 regulation of monoatomic ion transport
•              GO:0051049 regulation of transport
•              GO:0050896 response to stimulus
•              GO:0023052 signaling
•              GO:0055085 transmembrane transport
•              GO:0022857 transmembrane transporter activity
•              GO:0006810 transport
•                  GO:0055074 calcium ion homeostasis
•                  GO:0015085 calcium ion transmembrane transporter activity
•                  GO:0006816 calcium ion transport
•                  GO:0110165 cellular anatomical entity
•                  GO:0051641 cellular localization
•                  GO:0051716 cellular response to stimulus
•                  GO:0098660 inorganic ion transmembrane transport
•                  GO:0015318 inorganic molecular entity transmembrane transporter activity
•                  GO:0030003 intracellular monoatomic cation homeostasis
•                  GO:0022834 ligand-gated channel activity
•                  GO:0015276 ligand-gated monoatomic ion channel activity
•                  GO:0051235 maintenance of location
•                  GO:0005261 monoatomic cation channel activity
•                  GO:0006812 monoatomic cation transport
•                  GO:0022839 monoatomic ion gated channel activity
•                  GO:0034220 monoatomic ion transmembrane transport
•                  GO:0048519 negative regulation of biological process
•                  GO:0048523 negative regulation of cellular process
•                  GO:0051051 negative regulation of transport
•                  GO:0071702 organic substance transport
•                  GO:0022803 passive transmembrane transporter activity
•                  GO:0010646 regulation of cell communication
•                  GO:0010959 regulation of metal ion transport
•                  GO:0065009 regulation of molecular function
•                  GO:0048583 regulation of response to stimulus
•                  GO:0023051 regulation of signaling
•                  GO:0034762 regulation of transmembrane transport
•                  GO:0032409 regulation of transporter activity
•                  GO:0007165 signal transduction
•                  GO:0005215 transporter activity
•                      GO:0005262 calcium channel activity
•                      GO:0070588 calcium ion transmembrane transport
•                      GO:0019722 calcium-mediated signaling
•                      GO:0098662 inorganic cation transmembrane transport
•                      GO:0022890 inorganic cation transmembrane transporter activity
•                      GO:0005622 intracellular anatomical structure
•                      GO:0006874 intracellular calcium ion homeostasis
•                      GO:0035556 intracellular signal transduction
•                      GO:0099094 ligand-gated monoatomic cation channel activity
•                      GO:0051651 maintenance of location in cell
•                      GO:0098655 monoatomic cation transmembrane transport
•                      GO:0008324 monoatomic cation transmembrane transporter activity
•                      GO:0015075 monoatomic ion transmembrane transporter activity
•                      GO:0010648 negative regulation of cell communication
•                      GO:0044092 negative regulation of molecular function
•                      GO:0043271 negative regulation of monoatomic ion transport
•                      GO:0048585 negative regulation of response to stimulus
•                      GO:0023057 negative regulation of signaling
•                      GO:0034763 negative regulation of transmembrane transport
•                      GO:0048518 positive regulation of biological process
•                      GO:0051924 regulation of calcium ion transport
•                      GO:1904062 regulation of monoatomic cation transmembrane transport
•                      GO:0034765 regulation of monoatomic ion transmembrane transport
•                      GO:0051282 regulation of sequestering of calcium ion
•                      GO:0009966 regulation of signal transduction
•                      GO:0022898 regulation of transmembrane transporter activity
•                      GO:0051208 sequestering of calcium ion
•                          GO:0097553 calcium ion transmembrane import into cytosol
•                          GO:0005217 intracellular ligand-gated monoatomic ion channel activity
•                          GO:0099604 ligand-gated calcium channel activity
•                          GO:0046873 metal ion transmembrane transporter activity
•                          GO:0051926 negative regulation of calcium ion transport
•                          GO:1904063 negative regulation of cation transmembrane transport
•                          GO:0034766 negative regulation of monoatomic ion transmembrane transport
•                          GO:0051283 negative regulation of sequestering of calcium ion
•                          GO:0009968 negative regulation of signal transduction
•                          GO:0032410 negative regulation of transporter activity
•                          GO:0048522 positive regulation of cellular process
•                          GO:1903169 regulation of calcium ion transmembrane transport
•                          GO:1902531 regulation of intracellular signal transduction
•                          GO:0032412 regulation of monoatomic ion transmembrane transporter activity
•                          GO:0051209 release of sequestered calcium ion into cytosol
•                          GO:1901702 salt transmembrane transporter activity
•                          GO:0019932 second-messenger-mediated signaling
•                              GO:0015278 calcium-release channel activity
•                              GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
•                              GO:0048016 inositol phosphate-mediated signaling
•                              GO:1903170 negative regulation of calcium ion transmembrane transport
•                              GO:1902532 negative regulation of intracellular signal transduction
•                              GO:0032413 negative regulation of ion transmembrane transporter activity
•                              GO:0051284 positive regulation of sequestering of calcium ion
•                              GO:1901019 regulation of calcium ion transmembrane transporter activity
•                              GO:0050848 regulation of calcium-mediated signaling
•                              GO:2001257 regulation of cation channel activity
•                              GO:0051279 regulation of release of sequestered calcium ion into cytosol
•                                  GO:1901020 negative regulation of calcium ion transmembrane transporter activity
•                                  GO:0050849 negative regulation of calcium-mediated signaling
•                                  GO:2001258 negative regulation of cation channel activity
•                                  GO:0051280 negative regulation of release of sequestered calcium ion into cytosol
•                                  GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
•                                      GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Parents of negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031586)

subject	relation	object
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	is_a	negative regulation of calcium ion transmembrane transporter activity (GO:1901020)
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	is_a	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031585)
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	is_a	negative regulation of release of sequestered calcium ion into cytosol (GO:0051280)
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	RO:0002212	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0005220)
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	is_a	negative regulation of cation channel activity (GO:2001258)
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	is_a	negative regulation of calcium-mediated signaling (GO:0050849)

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