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Term Information

Accession
GO:0031261
Name
DNA replication preinitiation complex
Ontology
cellular_component
Synonyms
pre-IC
Alternate IDs
None
Definition
A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. Source: GOC:rb, GOC:jl, GOC:pr, GOC:vw, GOC:bf, GOC:hjd, PMID:15194812, PMID:17230184, PMID:12694535
Comment
None
History
See term history for GO:0031261 at QuickGO
Subset
None
Feedback
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Graph of GO:0031261

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Parents of DNA replication preinitiation complex (GO:0031261)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA replication preinitiation complex [is_a relation] is_a  protein-DNA complex (GO:0032993)
DNA replication preinitiation complex [BFO:0000051 relation] BFO:0000051  nuclear pre-replicative complex (GO:0005656)
DNA replication preinitiation complex [BFO:0000050 relation] BFO:0000050  nucleoplasm (GO:0005654)
Children of DNA replication preinitiation complex (GO:0031261)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
CMG complex (GO:0071162) [is_a relation] is_a  DNA replication preinitiation complex
GINS complex (GO:0000811) [is_a relation] is_a  DNA replication preinitiation complex
None.