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establishment or maintenance of heterochromatin architecture
Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
Note that this term refers to breakage of chromosomes during normal DNA rearrangements characteristic of ciliates; it is not to be used for DNA damage or other abnormal occurrences.