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Term Information

Accession
GO:0030968
Name
endoplasmic reticulum unfolded protein response
Ontology
biological_process
Synonyms
ER unfolded protein response, erUPR, SREBP-mediated signalling pathway
Alternate IDs
None
Definition
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. Source: GOC:mah, PMID:12042763
Comment
Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'.
History
See term history for GO:0030968 at QuickGO
Subset
None
Feedback
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Graph of GO:0030968

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Parents of endoplasmic reticulum unfolded protein response (GO:0030968)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
endoplasmic reticulum unfolded protein response [is_a relation] is_a  signal transduction (GO:0007165)
endoplasmic reticulum unfolded protein response [is_a relation] is_a  response to endoplasmic reticulum stress (GO:0034976)
endoplasmic reticulum unfolded protein response [BFO:0000050 relation] BFO:0000050  cellular response to unfolded protein (GO:0034620)
Children of endoplasmic reticulum unfolded protein response (GO:0030968)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response (GO:0006990) [BFO:0000050 relation] BFO:0000050  endoplasmic reticulum unfolded protein response
PERK-mediated unfolded protein response (GO:0036499) [is_a relation] is_a  endoplasmic reticulum unfolded protein response
IRE1-mediated unfolded protein response (GO:0036498) [is_a relation] is_a  endoplasmic reticulum unfolded protein response
negative regulation of endoplasmic reticulum unfolded protein response (GO:1900102) [RO:0002212 relation] RO:0002212  endoplasmic reticulum unfolded protein response
regulation of endoplasmic reticulum unfolded protein response (GO:1900101) [RO:0002211 relation] RO:0002211  endoplasmic reticulum unfolded protein response
positive regulation of endoplasmic reticulum unfolded protein response (GO:1900103) [RO:0002213 relation] RO:0002213  endoplasmic reticulum unfolded protein response
ATF6-mediated unfolded protein response (GO:0036500) [is_a relation] is_a  endoplasmic reticulum unfolded protein response
None.