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Term Information

Accession
GO:0030057
Name
desmosome
Ontology
cellular_component
Synonyms
macula adherens, spot desmosome
Alternate IDs
None
Definition
A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. Source: GOC:mtg_muscle, GOC:mah, ISBN:0815332181
Comment
None
History
See term history for GO:0030057 at QuickGO
Subset
None
Feedback
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Graph of GO:0030057

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Parents of desmosome (GO:0030057)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
desmosome [is_a relation] is_a  cell-cell junction (GO:0005911)
Children of desmosome (GO:0030057)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
outer dense plaque of desmosome (GO:0090636) [BFO:0000050 relation] BFO:0000050  desmosome
extracellular core region of desmosome (GO:0090635) [BFO:0000050 relation] BFO:0000050  desmosome
inner dense plaque of desmosome (GO:0090637) [BFO:0000050 relation] BFO:0000050  desmosome
Wikipedia
Desmosome