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Term Information

Accession
GO:0019342
Name
trypanothione biosynthetic process
Ontology
biological_process
Synonyms
trypanothione anabolism, trypanothione biosynthesis, trypanothione formation, trypanothione synthesis
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress. Source: MetaCyc:TRYPANOSYN-PWY, PMID:9677355
Comment
None
History
See term history for GO:0019342 at QuickGO
Subset
None
Feedback
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Graph of GO:0019342

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Parents of trypanothione biosynthetic process (GO:0019342)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
trypanothione biosynthetic process [is_a relation] is_a  trypanothione metabolic process (GO:0046206)
trypanothione biosynthetic process [is_a relation] is_a  glutathione derivative biosynthetic process (GO:1901687)
Children of trypanothione biosynthetic process (GO:0019342)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of trypanothione biosynthetic process (GO:1905724) [RO:0002213 relation] RO:0002213  trypanothione biosynthetic process
regulation of trypanothione biosynthetic process (GO:1905722) [RO:0002211 relation] RO:0002211  trypanothione biosynthetic process
negative regulation of trypanothione biosynthetic process (GO:1905723) [RO:0002212 relation] RO:0002212  trypanothione biosynthetic process
MetaCyc
TRYPANOSYN-PWY