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Term Information

Accession
GO:0017121
Name
plasma membrane phospholipid scrambling
Ontology
biological_process
Synonyms
PL scrambling, phospholipid scrambling
Alternate IDs
None
Definition
The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). Source: PMID:20302864, PMID:20043909, GOC:cjm
Comment
Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.
History
See term history for GO:0017121 at QuickGO
Subset
None
Feedback
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Graph of GO:0017121

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Parents of plasma membrane phospholipid scrambling (GO:0017121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
plasma membrane phospholipid scrambling [is_a relation] is_a  phospholipid translocation (GO:0045332)
plasma membrane phospholipid scrambling [is_a relation] is_a  plasma membrane organization (GO:0007009)
Children of plasma membrane phospholipid scrambling (GO:0017121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphatidylserine exposure on osteoblast involved in bone mineralization (GO:0061592) [is_a relation] is_a  plasma membrane phospholipid scrambling
calcium activated phospholipid scrambling (GO:0061588) [is_a relation] is_a  plasma membrane phospholipid scrambling
phospholipid scramblase activity (GO:0017128) [BFO:0000050 relation] BFO:0000050  plasma membrane phospholipid scrambling
phosphatidylserine exposure on apoptotic cell surface (GO:0070782) [is_a relation] is_a  plasma membrane phospholipid scrambling
phosphatidylserine exposure on blood platelet (GO:0097045) [is_a relation] is_a  plasma membrane phospholipid scrambling
None.