Planteome: Term Details for "plasma membrane phospholipid scrambling" (GO:0017121)

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Term Information

Accession: GO:0017121
Name: plasma membrane phospholipid scrambling
Ontology: biological_process
Synonyms: PL scrambling, phospholipid scrambling
Alternate IDs: None
Definition: The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). Source: PMID:20302864, PMID:20043909, GOC:cjm
Comment: Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.
History: See term history for GO:0017121 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to plasma membrane phospholipid scrambling.; Link to all direct and indirect annotations to plasma membrane phospholipid scrambling.; Link to all direct and indirect annotations download (limited to first 10,000) for plasma membrane phospholipid scrambling.
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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0051179 localization
BFO:0000015 process
GO:0051234 establishment of localization
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0033036 macromolecule localization
GO:0006810 transport
GO:0071840 cellular component organization or biogenesis
GO:0010876 lipid localization
GO:0061024 membrane organization
GO:0071702 organic substance transport
GO:0065008 regulation of biological quality
GO:0016043 cellular component organization
GO:0006869 lipid transport
GO:0015748 organophosphate ester transport
GO:0097035 regulation of membrane lipid distribution
GO:0010256 endomembrane system organization
GO:0034204 lipid translocation
GO:0015914 phospholipid transport
GO:0045332 phospholipid translocation
GO:0007009 plasma membrane organization
GO:0017121 plasma membrane phospholipid scrambling
GO:0061588 calcium activated phospholipid scrambling
GO:0070782 phosphatidylserine exposure on apoptotic cell surface
GO:0097045 phosphatidylserine exposure on blood platelet
GO:0061592 phosphatidylserine exposure on osteoblast involved in bone mineralization
GO:0017128 phospholipid scramblase activity

Parents of plasma membrane phospholipid scrambling (GO:0017121)

subject	relation	object
plasma membrane phospholipid scrambling	is_a	phospholipid translocation (GO:0045332)
plasma membrane phospholipid scrambling	is_a	plasma membrane organization (GO:0007009)

Children of plasma membrane phospholipid scrambling (GO:0017121)

subject	relation	object
phosphatidylserine exposure on apoptotic cell surface (GO:0070782)	is_a	plasma membrane phospholipid scrambling
phosphatidylserine exposure on osteoblast involved in bone mineralization (GO:0061592)	is_a	plasma membrane phospholipid scrambling
phosphatidylserine exposure on blood platelet (GO:0097045)	is_a	plasma membrane phospholipid scrambling
calcium activated phospholipid scrambling (GO:0061588)	is_a	plasma membrane phospholipid scrambling
phospholipid scramblase activity (GO:0017128)	BFO:0000050	plasma membrane phospholipid scrambling