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Term Information

Accession
GO:0017077
Name
oxidative phosphorylation uncoupler activity
Ontology
molecular_function
Synonyms
mitochondrial uncoupling protein activity, uncoupling protein activity
Alternate IDs
GO:0015302
Definition
Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. Source: PMID:16179945, PMID:15738989
Comment
None
History
See term history for GO:0017077 at QuickGO
Subset
None
Feedback
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Graph of GO:0017077

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Parents of oxidative phosphorylation uncoupler activity (GO:0017077)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
oxidative phosphorylation uncoupler activity [is_a relation] is_a  transmembrane transporter activity (GO:0022857)
oxidative phosphorylation uncoupler activity [BFO:0000050 relation] BFO:0000050  proton transmembrane transport (GO:1902600)
Children of oxidative phosphorylation uncoupler activity (GO:0017077)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of oxidative phosphorylation uncoupler activity (GO:2000277) [RO:0002213 relation] RO:0002213  oxidative phosphorylation uncoupler activity
negative regulation of oxidative phosphorylation uncoupler activity (GO:2000276) [RO:0002212 relation] RO:0002212  oxidative phosphorylation uncoupler activity
regulation of oxidative phosphorylation uncoupler activity (GO:2000275) [RO:0002211 relation] RO:0002211  oxidative phosphorylation uncoupler activity
None.