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Term Information

Accession
GO:0016987
Name
sigma factor activity
Ontology
molecular_function
Synonyms
DNA-dependent RNA polymerase promoter selection factor, core DNA-dependent RNA polymerase binding promoter specificity activity, sigma factor activity, sigma transcription factor, bacterial sigma factor activity, plastid sigma factor activity, promoter selection factor activity
Alternate IDs
GO:0000996, GO:0001053
Definition
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. Source: GOC:txnOH-2018
Comment
None
History
See term history for GO:0016987 at QuickGO
Subset
None
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Graph of GO:0016987

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Parents of sigma factor activity (GO:0016987)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sigma factor activity [BFO:0000050 relation] BFO:0000050  regulation of DNA-templated transcription, initiation (GO:2000142)
sigma factor activity [BFO:0000051 relation] BFO:0000051  RNA polymerase core enzyme binding (GO:0043175)
sigma factor activity [is_a relation] is_a  transcription regulator activity (GO:0140110)
sigma factor activity [BFO:0000051 relation] BFO:0000051  core promoter sequence-specific DNA binding (GO:0001046)

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