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Term Information

Accession
GO:0016591
Name
RNA polymerase II, holoenzyme
Ontology
cellular_component
Synonyms
DNA-directed RNA polymerase II, holoenzyme
Alternate IDs
None
Definition
A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters. Source: GOC:krc, Wikipedia:Rna_polymerase_ii, GOC:jl, PMID:16858867
Comment
None
History
See term history for GO:0016591 at QuickGO
Subset
goslim_pir
Feedback
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Graph of GO:0016591

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Parents of RNA polymerase II, holoenzyme (GO:0016591)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase II, holoenzyme [BFO:0000050 relation] BFO:0000050  nucleoplasm (GO:0005654)
RNA polymerase II, holoenzyme [is_a relation] is_a  nuclear DNA-directed RNA polymerase complex (GO:0055029)
Children of RNA polymerase II, holoenzyme (GO:0016591)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Cdc73/Paf1 complex (GO:0016593) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFIIH holo complex (GO:0005675) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFTC complex (GO:0033276) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFIIA complex (GO:0005672) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
RNA polymerase II, core complex (GO:0005665) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFIIF complex (GO:0005674) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFIIE complex (GO:0005673) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
transcription factor TFIID complex (GO:0005669) [BFO:0000050 relation] BFO:0000050  RNA polymerase II, holoenzyme
None.