You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Term Information

Accession
GO:0016246
Name
RNA interference
Ontology
biological_process
Synonyms
RNAi, posttranscriptional gene silencing by siRNA
Alternate IDs
None
Definition
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. Source: GOC:ems, PMID:11713190, PMID:11201747, PMID:18771919
Comment
Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'.
History
See term history for GO:0016246 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
External term view.

Graph of GO:0016246

Viewing options
Parents of RNA interference (GO:0016246)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA interference [is_a relation] is_a  post-transcriptional gene silencing by RNA (GO:0035194)
Children of RNA interference (GO:0016246)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transitive RNA interference (GO:0036453) [is_a relation] is_a  RNA interference
siRNA loading onto RISC involved in RNA interference (GO:0035087) [BFO:0000050 relation] BFO:0000050  RNA interference
production of siRNA involved in RNA interference (GO:0030422) [BFO:0000050 relation] BFO:0000050  RNA interference
positive regulation of RNA interference (GO:1900370) [RO:0002213 relation] RO:0002213  RNA interference
targeting of mRNA for destruction involved in RNA interference (GO:0030423) [BFO:0000050 relation] BFO:0000050  RNA interference
negative regulation of translation involved in RNA interference (GO:0070549) [BFO:0000050 relation] BFO:0000050  RNA interference
mRNA cleavage involved in gene silencing by siRNA (GO:0090625) [BFO:0000050 relation] BFO:0000050  RNA interference
RNA interference involved in olfactory learning (GO:1903453) [is_a relation] is_a  RNA interference
regulation of RNA interference (GO:1900368) [RO:0002211 relation] RO:0002211  RNA interference
negative regulation of RNA interference (GO:1900369) [RO:0002212 relation] RO:0002212  RNA interference
production of lsiRNA involved in RNA interference (GO:0010599) [BFO:0000050 relation] BFO:0000050  RNA interference
Wikipedia
RNA_interference