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Term Information

Accession
GO:0016174
Name
NAD(P)H oxidase H2O2-forming activity
Ontology
molecular_function
Synonyms
NAD(P)H:oxygen oxidoreductase activity, dual oxidase activity, p138tox, THOX2 activity, ThOX activity, thyroid NADPH oxidase activity, thyroid oxidase 2 activity, thyroid oxidase activity, NAD(P)H oxidase activity, NADPH oxidase
Alternate IDs
None
Definition
Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. Source: PMID:10401672, PMID:11822874, EC:1.6.3.1, PMID:10601291, RHEA:11260
Comment
None
History
See term history for GO:0016174 at QuickGO
Subset
None
Feedback
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Graph of GO:0016174

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Parents of NAD(P)H oxidase H2O2-forming activity (GO:0016174)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NAD(P)H oxidase H2O2-forming activity [is_a relation] is_a  oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor (GO:0050664)
Children of NAD(P)H oxidase H2O2-forming activity (GO:0016174)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NADPH oxidase H202-forming activity (GO:0106294) [is_a relation] is_a  NAD(P)H oxidase H2O2-forming activity
NADH oxidase H202-forming activity (GO:0106293) [is_a relation] is_a  NAD(P)H oxidase H2O2-forming activity
negative regulation of NAD(P)H oxidase activity (GO:0033861) [RO:0002212 relation] RO:0002212  NAD(P)H oxidase H2O2-forming activity
regulation of NAD(P)H oxidase activity (GO:0033860) [RO:0002211 relation] RO:0002211  NAD(P)H oxidase H2O2-forming activity
positive regulation of NAD(P)H oxidase activity (GO:0033864) [RO:0002213 relation] RO:0002213  NAD(P)H oxidase H2O2-forming activity
EC
1.6.3.1
Reactome
R-HSA-5693681