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Term Information

Accession
GO:0015039
Name
NADPH-adrenodoxin reductase activity
Ontology
molecular_function
Synonyms
adrenodoxin-type ferredoxin reductase activity, NADPH:adrenodoxin oxidoreductase activity, adrenodoxin reductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+. Source: RHEA:42312, GOC:kd
Comment
Note that this term specifically refers to the reaction proceeding in the direction shown; under physiological conditions adrenodoxin reduction by adrenodoxin reductase is coupled with electron transfer from AdR to P450, which catalyzes an irreversible monooxygenation reaction. This term should therefore be used to annotate gene products that catalyze the reduction of oxidized adrenodoxin; also consider annotating to the molecular function term 'ferredoxin-NADP+ reductase activity ; GO:0004324'.
History
See term history for GO:0015039 at QuickGO
Subset
None
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Graph of GO:0015039

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Parents of NADPH-adrenodoxin reductase activity (GO:0015039)
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NADPH-adrenodoxin reductase activity [is_a relation] is_a  oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor (GO:0016731)

This term has no children.

EC
1.18.1.6
MetaCyc
RXN-13685
RHEA
42312