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Term Information

Accession
GO:0015012
Name
heparan sulfate proteoglycan biosynthetic process
Ontology
biological_process
Synonyms
heparan sulfate proteoglycan anabolism, heparan sulfate proteoglycan biosynthesis, heparan sulfate proteoglycan formation, heparan sulfate proteoglycan synthesis, heparan sulphate proteoglycan biosynthesis, heparan sulphate proteoglycan biosynthetic process, heparin proteoglycan biosynthetic process
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. Source: ISBN:0198506732, ISBN:0198547684, RESID:AA0210, GOC:mah
Comment
None
History
See term history for GO:0015012 at QuickGO
Subset
None
Feedback
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Graph of GO:0015012

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Parents of heparan sulfate proteoglycan biosynthetic process (GO:0015012)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
heparan sulfate proteoglycan biosynthetic process [is_a relation] is_a  heparan sulfate proteoglycan metabolic process (GO:0030201)
heparan sulfate proteoglycan biosynthetic process [is_a relation] is_a  proteoglycan biosynthetic process (GO:0030166)
Children of heparan sulfate proteoglycan biosynthetic process (GO:0015012)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide (GO:0015013) [BFO:0000050 relation] BFO:0000050  heparan sulfate proteoglycan biosynthetic process
regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010908) [RO:0002211 relation] RO:0002211  heparan sulfate proteoglycan biosynthetic process
heparan sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0015015) [BFO:0000050 relation] BFO:0000050  heparan sulfate proteoglycan biosynthetic process
positive regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010909) [RO:0002213 relation] RO:0002213  heparan sulfate proteoglycan biosynthetic process
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process (GO:0015014) [BFO:0000050 relation] BFO:0000050  heparan sulfate proteoglycan biosynthetic process
RESID
AA0210