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Term Information

Accession
GO:0008626
Name
granzyme-mediated apoptotic signaling pathway
Ontology
biological_process
Synonyms
apoptotic signaling pathway in response to granzyme, induction of apoptosis by granzyme
Alternate IDs
None
Definition
The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. Source: GOC:mtg_apoptosis, PMID:17158907
Comment
None
History
See term history for GO:0008626 at QuickGO
Subset
None
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Graph of GO:0008626

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Parents of granzyme-mediated apoptotic signaling pathway (GO:0008626)
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granzyme-mediated apoptotic signaling pathway [is_a relation] is_a  apoptotic signaling pathway (GO:0097190)
granzyme-mediated apoptotic signaling pathway [is_a relation] is_a  granzyme-mediated programmed cell death signaling pathway (GO:0140507)

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