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Term Information

Accession
GO:0008545
Name
JUN kinase kinase activity
Ontology
molecular_function
Synonyms
JNKK
Alternate IDs
None
Definition
Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. Source: PMID:11790549, GOC:bf, PMID:11057897
Comment
None
History
See term history for GO:0008545 at QuickGO
Subset
None
Feedback
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Graph of GO:0008545

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Parents of JUN kinase kinase activity (GO:0008545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
JUN kinase kinase activity [BFO:0000050 relation] BFO:0000050  activation of JUN kinase activity (GO:0007257)
JUN kinase kinase activity [is_a relation] is_a  MAP kinase kinase activity (GO:0004708)
Children of JUN kinase kinase activity (GO:0008545)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
activation of JNKK activity (GO:0007256) [RO:0002213 relation] RO:0002213  JUN kinase kinase activity
Reactome
R-HSA-168162