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Term Information

Accession
GO:0008349
Name
MAP kinase kinase kinase kinase activity
Ontology
molecular_function
Synonyms
MAP4K activity, MAPKKKK
Alternate IDs
None
Definition
Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli. Source: PMID:11790549, GOC:bf
Comment
None
History
See term history for GO:0008349 at QuickGO
Subset
None
Feedback
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Graph of GO:0008349

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Parents of MAP kinase kinase kinase kinase activity (GO:0008349)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MAP kinase kinase kinase kinase activity [BFO:0000050 relation] BFO:0000050  activation of MAPKKK activity (GO:0000185)
MAP kinase kinase kinase kinase activity [BFO:0000050 relation] BFO:0000050  MAPK cascade (GO:0000165)
MAP kinase kinase kinase kinase activity [is_a relation] is_a  protein serine/threonine kinase activity (GO:0004674)
Children of MAP kinase kinase kinase kinase activity (GO:0008349)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
JUN kinase kinase kinase kinase activity (GO:0042656) [is_a relation] is_a  MAP kinase kinase kinase kinase activity