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COP9 signalosome
Term Information
Accession
GO:0008180
Name
COP9 signalosome
Ontology
cellular_component
Synonyms
COP9 complex, CSN, signalosome
Alternate IDs
None
Definition
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
Source:PMID:12186635,
PMID:14570571,
PMID:11019806
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