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Term Information

Accession
GO:0008021
Name
synaptic vesicle
Ontology
cellular_component
Synonyms
docked vesicle
Alternate IDs
None
Definition
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. Source: PMID:12563290, PMID:10099709
Comment
This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.
History
See term history for GO:0008021 at QuickGO
Subset
goslim_synapse
Feedback
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Graph of GO:0008021

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Parents of synaptic vesicle (GO:0008021)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
synaptic vesicle [BFO:0000050 relation] BFO:0000050  presynapse (GO:0098793)
synaptic vesicle [is_a relation] is_a  exocytic vesicle (GO:0070382)
Children of synaptic vesicle (GO:0008021)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
synaptic vesicle lumen (GO:0034592) [BFO:0000050 relation] BFO:0000050  synaptic vesicle
synaptic vesicle, recycling pool (GO:1990475) [is_a relation] is_a  synaptic vesicle
synaptic vesicle, readily releasable pool (GO:1990474) [is_a relation] is_a  synaptic vesicle
synaptic vesicle, resting pool (GO:1990476) [is_a relation] is_a  synaptic vesicle
synaptic vesicle membrane (GO:0030672) [BFO:0000050 relation] BFO:0000050  synaptic vesicle
NIF_Subcellular
sao1071221672
Wikipedia
Synaptic_vesicle