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Term Information

Accession
GO:0008009
Name
chemokine activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. Source: PMID:12183377, GOC:BHF, Wikipedia:Chemokine, GOC:rl
Comment
None
History
See term history for GO:0008009 at QuickGO
Subset
goslim_chembl
Feedback
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Graph of GO:0008009

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Parents of chemokine activity (GO:0008009)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chemokine activity [is_a relation] is_a  cytokine activity (GO:0005125)
chemokine activity [BFO:0000050 relation] BFO:0000050  cell chemotaxis (GO:0060326)
chemokine activity [is_a relation] is_a  chemokine receptor binding (GO:0042379)
Children of chemokine activity (GO:0008009)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of chemokine activity (GO:1900136) [RO:0002211 relation] RO:0002211  chemokine activity
negative regulation of chemokine activity (GO:1900137) [RO:0002212 relation] RO:0002212  chemokine activity
None.