Planteome: Term Details for "I-kappaB phosphorylation" (GO:0007252)

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Term Information

Accession: GO:0007252
Name: I-kappaB phosphorylation
Ontology: biological_process
Synonyms: IKB phosphorylation, IkappaB phosphorylation, inhibitor of NF-kappaB phosphorylation, inhibitor of kappaB phosphorylation
Alternate IDs: None
Definition: The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. Source: PMID:7594468, GOC:jl, GOC:bf, PMID:21772278
Comment: None
History: See term history for GO:0007252 at QuickGO
Subset: gocheck_do_not_annotate
Related: Link to all annotated objects annotated to I-kappaB phosphorylation.; Link to all direct and indirect annotations to I-kappaB phosphorylation.; Link to all direct and indirect annotations download (limited to first 10,000) for I-kappaB phosphorylation.
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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0008152 metabolic process
BFO:0000015 process
GO:0044237 cellular metabolic process
GO:0005575 cellular_component
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0043170 macromolecule metabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0006793 phosphorus metabolic process
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0005622 intracellular anatomical structure
GO:0043412 macromolecule modification
GO:0006796 phosphate-containing compound metabolic process
GO:0019538 protein metabolic process
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
GO:0016310 phosphorylation
GO:0036211 protein modification process
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0006468 protein phosphorylation
GO:0007252 I-kappaB phosphorylation
GO:0008384 IkappaB kinase activity
GO:1903720 negative regulation of I-kappaB phosphorylation
GO:1903721 positive regulation of I-kappaB phosphorylation
GO:1903719 regulation of I-kappaB phosphorylation

Parents of I-kappaB phosphorylation (GO:0007252)

subject	relation	object
I-kappaB phosphorylation	BFO:0000050	I-kappaB kinase/NF-kappaB signaling (GO:0007249)
I-kappaB phosphorylation	is_a	protein phosphorylation (GO:0006468)

Children of I-kappaB phosphorylation (GO:0007252)

subject	relation	object
regulation of I-kappaB phosphorylation (GO:1903719)	RO:0002211	I-kappaB phosphorylation
negative regulation of I-kappaB phosphorylation (GO:1903720)	RO:0002212	I-kappaB phosphorylation
IkappaB kinase activity (GO:0008384)	BFO:0000050	I-kappaB phosphorylation
positive regulation of I-kappaB phosphorylation (GO:1903721)	RO:0002213	I-kappaB phosphorylation