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Term Information

Accession
GO:0007224
Name
smoothened signaling pathway
Ontology
biological_process
Synonyms
hedgehog signaling pathway, smoothened signalling pathway, Shh signaling pathway, Sonic hedgehog signaling pathway, hh signaling pathway, hh signalling pathway
Alternate IDs
None
Definition
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. Source: PMID:15205520, GOC:mah
Comment
None
History
See term history for GO:0007224 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0007224

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Parents of smoothened signaling pathway (GO:0007224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
smoothened signaling pathway [is_a relation] is_a  cell surface receptor signaling pathway (GO:0007166)
Children of smoothened signaling pathway (GO:0007224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ciliary receptor clustering involved in smoothened signaling pathway (GO:0060830) [BFO:0000050 relation] BFO:0000050  smoothened signaling pathway
regulation of smoothened signaling pathway (GO:0008589) [RO:0002211 relation] RO:0002211  smoothened signaling pathway
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation (GO:0021938) [is_a relation] is_a  smoothened signaling pathway
positive regulation of smoothened signaling pathway (GO:0045880) [RO:0002213 relation] RO:0002213  smoothened signaling pathway
smoothened signaling pathway involved in growth plate cartilage chondrocyte development (GO:0003435) [is_a relation] is_a  smoothened signaling pathway
smoothened signaling pathway involved in lung development (GO:0060506) [is_a relation] is_a  smoothened signaling pathway
mesenchymal smoothened signaling pathway involved in prostate gland development (GO:0060783) [is_a relation] is_a  smoothened signaling pathway
signal transduction downstream of smoothened (GO:0007227) [BFO:0000050 relation] BFO:0000050  smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:0060831) [is_a relation] is_a  smoothened signaling pathway
negative regulation of smoothened signaling pathway (GO:0045879) [RO:0002212 relation] RO:0002212  smoothened signaling pathway
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003271) [is_a relation] is_a  smoothened signaling pathway
smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021910) [is_a relation] is_a  smoothened signaling pathway