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Term Information

Accession
GO:0007188
Name
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Ontology
biological_process
Synonyms
G protein signaling, coupled to cAMP nucleotide second messenger, G protein signaling, coupled to cyclic AMP nucleotide second messenger, G protein signalling, coupled to cAMP nucleotide second messenger, G protein signalling, coupled to cyclic AMP nucleotide second messenger, G-protein signaling, coupled to cAMP nucleotide second messenger, G-protein signaling, coupled to cyclic AMP nucleotide second messenger, G-protein signalling, coupled to cAMP nucleotide second messenger, G-protein signalling, coupled to cyclic AMP nucleotide second messenger, GPCR signaling pathway via cAMP second messenger, GPCR signaling pathway via modulation of adenylate cyclase activity, adenylate cyclase-modulating GPCR signaling pathway
Alternate IDs
None
Definition
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP). Source: GOC:signaling, GOC:mah, ISBN:0815316194
Comment
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to 'regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway ; GO:0010578.
History
See term history for GO:0007188 at QuickGO
Subset
None
Feedback
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Graph of GO:0007188

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Parents of adenylate cyclase-modulating G protein-coupled receptor signaling pathway (GO:0007188)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-modulating G protein-coupled receptor signaling pathway [BFO:0000051 relation] BFO:0000051  cAMP-mediated signaling (GO:0019933)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway [BFO:0000051 relation] BFO:0000051  regulation of cAMP-mediated signaling (GO:0043949)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway [is_a relation] is_a  G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway [BFO:0000051 relation] BFO:0000051  regulation of adenylate cyclase activity (GO:0045761)
Children of adenylate cyclase-modulating G protein-coupled receptor signaling pathway (GO:0007188)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (GO:0007193) [is_a relation] is_a  adenylate cyclase-modulating G protein-coupled receptor signaling pathway
adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189) [is_a relation] is_a  adenylate cyclase-modulating G protein-coupled receptor signaling pathway
regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway (GO:0010578) [BFO:0000050 relation] BFO:0000050  adenylate cyclase-modulating G protein-coupled receptor signaling pathway
None.