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Term Information

Accession
GO:0007186
Name
G protein-coupled receptor signaling pathway
Ontology
biological_process
Synonyms
G protein coupled receptor protein signaling pathway, G protein coupled receptor protein signalling pathway, G-protein coupled receptor protein signal transduction, G-protein coupled receptor protein signaling pathway, G-protein coupled receptor signalling pathway, G-protein-coupled receptor protein signalling pathway, GPCR signaling pathway, GPCR signalling pathway, G-protein coupled receptor signaling pathway via GPCR dimer, dimeric G-protein coupled receptor signaling pathway, dimeric G-protein coupled receptor signalling pathway
Alternate IDs
GO:0038042
Definition
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. Source: Wikipedia:G_protein-coupled_receptor, PMID:24568158, PMID:16902576, GOC:bf, GOC:mah
Comment
None
History
See term history for GO:0007186 at QuickGO
Subset
goslim_drosophila
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0007186

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Parents of G protein-coupled receptor signaling pathway (GO:0007186)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G protein-coupled receptor signaling pathway [is_a relation] is_a  signal transduction (GO:0007165)
Children of G protein-coupled receptor signaling pathway (GO:0007186)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of G protein-coupled receptor signaling pathway (GO:0008277) [RO:0002211 relation] RO:0002211  G protein-coupled receptor signaling pathway
octopamine or tyramine signaling pathway (GO:0007211) [is_a relation] is_a  G protein-coupled receptor signaling pathway
gastric inhibitory peptide signaling pathway (GO:0038192) [is_a relation] is_a  G protein-coupled receptor signaling pathway
negative regulation of G protein-coupled receptor signaling pathway (GO:0045744) [RO:0002212 relation] RO:0002212  G protein-coupled receptor signaling pathway
somatostatin receptor signaling pathway (GO:0038169) [is_a relation] is_a  G protein-coupled receptor signaling pathway
phospholipase D-activating G protein-coupled receptor signaling pathway (GO:0031583) [is_a relation] is_a  G protein-coupled receptor signaling pathway
rhodopsin mediated signaling pathway (GO:0016056) [is_a relation] is_a  G protein-coupled receptor signaling pathway
apelin receptor signaling pathway (GO:0060183) [is_a relation] is_a  G protein-coupled receptor signaling pathway
cholecystokinin signaling pathway (GO:0038188) [is_a relation] is_a  G protein-coupled receptor signaling pathway
bombesin receptor signaling pathway (GO:0031989) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling in absence of ligand (GO:0038035) [is_a relation] is_a  G protein-coupled receptor signaling pathway
angiotensin-activated signaling pathway (GO:0038166) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway involved in dauer larval development (GO:1904066) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor activity (GO:0004930) [BFO:0000050 relation] BFO:0000050  G protein-coupled receptor signaling pathway
follicle-stimulating hormone signaling pathway (GO:0042699) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway involved in social behavior (GO:1904068) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium (GO:1903554) [is_a relation] is_a  G protein-coupled receptor signaling pathway
sphingosine-1-phosphate receptor signaling pathway (GO:0003376) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled glutamate receptor signaling pathway (GO:0007216) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled purinergic receptor signaling pathway (GO:0035588) [is_a relation] is_a  G protein-coupled receptor signaling pathway
calcitonin family receptor signaling pathway (GO:0097646) [is_a relation] is_a  G protein-coupled receptor signaling pathway
gamma-aminobutyric acid signaling pathway (GO:0007214) [is_a relation] is_a  G protein-coupled receptor signaling pathway
tachykinin receptor signaling pathway (GO:0007217) [is_a relation] is_a  G protein-coupled receptor signaling pathway
adrenergic receptor signaling pathway (GO:0071875) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled serotonin receptor signaling pathway (GO:0098664) [is_a relation] is_a  G protein-coupled receptor signaling pathway
thrombin-activated receptor signaling pathway (GO:0070493) [is_a relation] is_a  G protein-coupled receptor signaling pathway
thyroid-stimulating hormone signaling pathway (GO:0038194) [is_a relation] is_a  G protein-coupled receptor signaling pathway
ion channel modulating, G protein-coupled receptor signaling pathway (GO:0099105) [is_a relation] is_a  G protein-coupled receptor signaling pathway
thromboxane A2 signaling pathway (GO:0038193) [is_a relation] is_a  G protein-coupled receptor signaling pathway
opioid receptor signaling pathway (GO:0038003) [is_a relation] is_a  G protein-coupled receptor signaling pathway
neuropeptide signaling pathway (GO:0007218) [is_a relation] is_a  G protein-coupled receptor signaling pathway
luteinizing hormone signaling pathway (GO:0042700) [is_a relation] is_a  G protein-coupled receptor signaling pathway
cannabinoid signaling pathway (GO:0038171) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled acetylcholine receptor signaling pathway (GO:0007213) [is_a relation] is_a  G protein-coupled receptor signaling pathway
phospholipase C-inhibiting G protein-coupled receptor signaling pathway (GO:0030845) [is_a relation] is_a  G protein-coupled receptor signaling pathway
ion channel regulator activity involved in G protein-coupled receptor signaling pathway (GO:0099107) [BFO:0000050 relation] BFO:0000050  G protein-coupled receptor signaling pathway
protein kinase C-activating G protein-coupled receptor signaling pathway (GO:0007205) [is_a relation] is_a  G protein-coupled receptor signaling pathway
positive regulation of G protein-coupled receptor signaling pathway (GO:0045745) [RO:0002213 relation] RO:0002213  G protein-coupled receptor signaling pathway
phospholipase C-activating G protein-coupled receptor signaling pathway (GO:0007200) [is_a relation] is_a  G protein-coupled receptor signaling pathway
complement component C5a signaling pathway (GO:0038178) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) [is_a relation] is_a  G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway involved in heart process (GO:0086103) [is_a relation] is_a  G protein-coupled receptor signaling pathway
endothelin receptor signaling pathway (GO:0086100) [is_a relation] is_a  G protein-coupled receptor signaling pathway
leukotriene signaling pathway (GO:0061737) [is_a relation] is_a  G protein-coupled receptor signaling pathway
None.