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Term Information

Accession
GO:0007173
Name
epidermal growth factor receptor signaling pathway
Ontology
biological_process
Synonyms
EGF receptor signaling pathway, EGF receptor signalling pathway, EGFR signaling pathway, ERBB1 signaling pathway, epidermal growth factor receptor signalling pathway, receptor tyrosine-protein kinase erbB-1 signaling pathway
Alternate IDs
None
Definition
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. Source: GOC:ceb
Comment
None
History
See term history for GO:0007173 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0007173

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Parents of epidermal growth factor receptor signaling pathway (GO:0007173)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epidermal growth factor receptor signaling pathway [is_a relation] is_a  ERBB signaling pathway (GO:0038127)
Children of epidermal growth factor receptor signaling pathway (GO:0007173)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epidermal growth factor signaling pathway involved in forebrain neuron fate commitment (GO:0022026) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor-activated receptor activity (GO:0005006) [BFO:0000050 relation] BFO:0000050  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway involved in heart process (GO:1905251) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway (GO:0042059) [RO:0002212 relation] RO:0002212  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway via MAPK cascade (GO:0038029) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
ERBB2-EGFR signaling pathway (GO:0038134) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
regulation of epidermal growth factor receptor signaling pathway (GO:0042058) [RO:0002211 relation] RO:0002211  epidermal growth factor receptor signaling pathway
ERBB4-EGFR signaling pathway (GO:0038137) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
gurken signaling pathway (GO:0008314) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway involved in lung development (GO:0060507) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity (GO:0038167) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) [RO:0002213 relation] RO:0002213  epidermal growth factor receptor signaling pathway
coreceptor activity involved in epidermal growth factor receptor signaling pathway (GO:0060724) [BFO:0000050 relation] BFO:0000050  epidermal growth factor receptor signaling pathway
None.