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Term Information

Accession
GO:0006342
Name
chromatin silencing
Ontology
biological_process
Synonyms
TGS, chromatin-mediated maintenance of transcriptional inactivation, chromatin-mediated silencing, transcriptional gene silencing, heterochromatic silencing
Alternate IDs
GO:0016440
Definition
Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. Source: PMID:10219245, GOC:mah
Comment
Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription.
History
See term history for GO:0006342 at QuickGO
Subset
None
Feedback
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Graph of GO:0006342

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Parents of chromatin silencing (GO:0006342)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chromatin silencing [is_a relation] is_a  negative regulation of gene expression, epigenetic (GO:0045814)
chromatin silencing [is_a relation] is_a  gene silencing (GO:0016458)
chromatin silencing [is_a relation] is_a  chromatin organization involved in negative regulation of transcription (GO:0097549)
chromatin silencing [is_a relation] is_a  negative regulation of transcription, DNA-templated (GO:0045892)
Children of chromatin silencing (GO:0006342)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chromatin silencing at telomere (GO:0006348) [is_a relation] is_a  chromatin silencing
transfer RNA gene-mediated silencing (GO:0061587) [is_a relation] is_a  chromatin silencing
regulation of chromatin silencing (GO:0031935) [RO:0002211 relation] RO:0002211  chromatin silencing
positive regulation of chromatin silencing (GO:0031937) [RO:0002213 relation] RO:0002213  chromatin silencing
heterochromatin organization involved in chromatin silencing (GO:0070868) [BFO:0000050 relation] BFO:0000050  chromatin silencing
negative regulation of chromatin silencing (GO:0031936) [RO:0002212 relation] RO:0002212  chromatin silencing
None.