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Term Information

Accession
GO:0006285
Name
base-excision repair, AP site formation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired. Source: ISBN:0815316194
Comment
None
History
See term history for GO:0006285 at QuickGO
Subset
None
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Graph of GO:0006285

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Parents of base-excision repair, AP site formation (GO:0006285)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
base-excision repair, AP site formation [is_a relation] is_a  DNA metabolic process (GO:0006259)
base-excision repair, AP site formation [BFO:0000050 relation] BFO:0000050  base-excision repair (GO:0006284)
Children of base-excision repair, AP site formation (GO:0006285)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
base-excision repair, AP site formation via deaminated base removal (GO:0097510) [is_a relation] is_a  base-excision repair, AP site formation
depyrimidination (GO:0045008) [is_a relation] is_a  base-excision repair, AP site formation
depurination (GO:0045007) [is_a relation] is_a  base-excision repair, AP site formation
None.