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Term Information

Accession
GO:0006127
Name
glycerophosphate shuttle
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle. Source: GOC:mtg_electron_transport, GOC:jl, PMID:16368075, ISBN:0716720094
Comment
None
History
See term history for GO:0006127 at QuickGO
Subset
None
Feedback
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Graph of GO:0006127

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Parents of glycerophosphate shuttle (GO:0006127)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glycerophosphate shuttle [is_a relation] is_a  cellular ketone metabolic process (GO:0042180)
glycerophosphate shuttle [is_a relation] is_a  organophosphate metabolic process (GO:0019637)
glycerophosphate shuttle [is_a relation] is_a  carbohydrate derivative metabolic process (GO:1901135)
glycerophosphate shuttle [is_a relation] is_a  NADH oxidation (GO:0006116)
glycerophosphate shuttle [BFO:0000051 relation] BFO:0000051  sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity (GO:0052590)
glycerophosphate shuttle [is_a relation] is_a  phosphate-containing compound metabolic process (GO:0006796)
glycerophosphate shuttle [BFO:0000051 relation] BFO:0000051  glycerol-3-phosphate dehydrogenase [NAD+] activity (GO:0004367)
glycerophosphate shuttle [BFO:0000050 relation] BFO:0000050  respiratory electron transport chain (GO:0022904)
glycerophosphate shuttle [is_a relation] is_a  primary alcohol metabolic process (GO:0034308)

This term has no children.

MetaCyc
PWY-6118