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Term Information

Accession
GO:0006099
Name
tricarboxylic acid cycle
Ontology
biological_process
Synonyms
Krebs cycle, TCA cycle, citric acid cycle
Alternate IDs
None
Definition
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. Source: ISBN:0198506732
Comment
None
History
See term history for GO:0006099 at QuickGO
Subset
None
Feedback
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Graph of GO:0006099

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Parents of tricarboxylic acid cycle (GO:0006099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tricarboxylic acid cycle [is_a relation] is_a  primary metabolic process (GO:0044238)
tricarboxylic acid cycle [BFO:0000050 relation] BFO:0000050  aerobic respiration (GO:0009060)
Children of tricarboxylic acid cycle (GO:0006099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
reductive tricarboxylic acid cycle (GO:0019643) [is_a relation] is_a  tricarboxylic acid cycle