Planteome: Term Details for "mitochondrial pyruvate dehydrogenase complex" (GO:0005967)

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Term Information

Accession: GO:0005967
Name: mitochondrial pyruvate dehydrogenase complex
Ontology: cellular_component
Synonyms: pyruvate dehydrogenase complex (lipoamide)
Alternate IDs: None
Definition: Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase. Source: ISBN:0471331309, GOC:mtg_sensu, ISBN:0716720094
Comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
History: See term history for GO:0005967 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to mitochondrial pyruvate dehydrogenase complex.; Link to all direct and indirect annotations to mitochondrial pyruvate dehydrogenase complex.; Link to all direct and indirect annotations download (limited to first 10,000) for mitochondrial pyruvate dehydrogenase complex.
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GO:0110165 cellular anatomical entity
GO:0043226 organelle
GO:0005575 cellular_component
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
GO:0043233 organelle lumen
GO:0070013 intracellular organelle lumen
GO:0005739 mitochondrion
GO:1990204 oxidoreductase complex
GO:0005759 mitochondrial matrix
GO:0098798 mitochondrial protein-containing complex
GO:0045254 pyruvate dehydrogenase complex
GO:0005967 mitochondrial pyruvate dehydrogenase complex

Parents of mitochondrial pyruvate dehydrogenase complex (GO:0005967)

subject	relation	object
mitochondrial pyruvate dehydrogenase complex	BFO:0000050	mitochondrial matrix (GO:0005759)
mitochondrial pyruvate dehydrogenase complex	is_a	pyruvate dehydrogenase complex (GO:0045254)
mitochondrial pyruvate dehydrogenase complex	is_a	mitochondrial protein-containing complex (GO:0098798)
mitochondrial pyruvate dehydrogenase complex	BFO:0000050	mitochondrion (GO:0005739)

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mitochondrial pyruvate dehydrogenase complex

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Parents of mitochondrial pyruvate dehydrogenase complex (GO:0005967)

None.