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Term Information

Accession
GO:0005942
Name
phosphatidylinositol 3-kinase complex
Ontology
cellular_component
Synonyms
1-phosphatidylinositol 3-kinase complex, PI3K complex, phosphoinositide 3-kinase complex, PI3-kinase p85-subunit alpha- PI3-kinase p110 complex, PIK3C3-PIK3R4 complex, PIK3CA-PIK3R1 complex
Alternate IDs
None
Definition
A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. Source: GOC:bf, PMID:24587488
Comment
For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/
History
See term history for GO:0005942 at QuickGO
Subset
goslim_pir
Feedback
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Graph of GO:0005942

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Parents of phosphatidylinositol 3-kinase complex (GO:0005942)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphatidylinositol 3-kinase complex [is_a relation] is_a  transferase complex, transferring phosphorus-containing groups (GO:0061695)
phosphatidylinositol 3-kinase complex [BFO:0000050 relation] BFO:0000050  extrinsic component of membrane (GO:0019898)
phosphatidylinositol 3-kinase complex [is_a relation] is_a  membrane protein complex (GO:0098796)
Children of phosphatidylinositol 3-kinase complex (GO:0005942)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphatidylinositol 3-kinase complex, class II (GO:0097652) [is_a relation] is_a  phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class III (GO:0035032) [is_a relation] is_a  phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class I (GO:0097651) [is_a relation] is_a  phosphatidylinositol 3-kinase complex
None.