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Term Information

Accession
GO:0005884
Name
actin filament
Ontology
cellular_component
Synonyms
microfilament
Alternate IDs
None
Definition
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. Source: ISBN:0198506732, GOC:mah, PMID:10666339
Comment
None
History
See term history for GO:0005884 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0005884

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Parents of actin filament (GO:0005884)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
actin filament [is_a relation] is_a  polymeric cytoskeletal fiber (GO:0099513)
actin filament [BFO:0000050 relation] BFO:0000050  actin cytoskeleton (GO:0015629)
Children of actin filament (GO:0005884)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
actin filament bundle (GO:0032432) [BFO:0000051 relation] BFO:0000051  actin filament
actin filament branch point (GO:0061834) [BFO:0000050 relation] BFO:0000050  actin filament
filamentous actin (GO:0031941) [BFO:0000050 relation] BFO:0000050  actin filament
actin-based cell projection (GO:0098858) [BFO:0000051 relation] BFO:0000051  actin filament
actomyosin contractile ring actin filament (GO:1903144) [is_a relation] is_a  actin filament
actin filament of cell cortex of cell tip (GO:1903145) [is_a relation] is_a  actin filament
actin wave (GO:0062201) [BFO:0000051 relation] BFO:0000051  actin filament
actin fusion focus (GO:1990819) [BFO:0000051 relation] BFO:0000051  actin filament
FMA
63850
NIF_Subcellular
sao1588493326
Wikipedia
Actin