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Term Information

Accession
GO:0005579
Name
membrane attack complex
Ontology
cellular_component
Synonyms
MAC, TCC, terminal complement complex, membrane attack complex protein alphaM chain, membrane attack complex protein beta2 chain
Alternate IDs
None
Definition
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Source: ISBN:0198547684, ISBN:0781735149, GOC:add, ISBN:068340007X
Comment
None
History
See term history for GO:0005579 at QuickGO
Subset
None
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Graph of GO:0005579

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Parents of membrane attack complex (GO:0005579)
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membrane attack complex [is_a relation] is_a  pore complex (GO:0046930)
membrane attack complex [is_a relation] is_a  plasma membrane protein complex (GO:0098797)

This term has no children.