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Term Information

Accession
GO:0005078
Name
MAP-kinase scaffold activity
Ontology
molecular_function
Synonyms
MAP-kinase scaffold protein activity
Alternate IDs
None
Definition
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. Source: PMID:15213240, PMID:12511654, PMID:9405336
Comment
None
History
See term history for GO:0005078 at QuickGO
Subset
None
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Graph of GO:0005078

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Parents of MAP-kinase scaffold activity (GO:0005078)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MAP-kinase scaffold activity [BFO:0000050 relation] BFO:0000050  positive regulation of MAPK cascade (GO:0043410)
MAP-kinase scaffold activity [is_a relation] is_a  kinase binding (GO:0019900)
MAP-kinase scaffold activity [is_a relation] is_a  signaling adaptor activity (GO:0035591)

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None.