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Term Information

Accession
GO:0005006
Name
epidermal growth factor-activated receptor activity
Ontology
molecular_function
Synonyms
EGF receptor activity, EGFR, TGF-alpha receptor activity, epidermal growth factor receptor activity, transforming growth factor-alpha receptor activity
Alternate IDs
GO:0005023
Definition
Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. Source: GOC:bf
Comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
History
See term history for GO:0005006 at QuickGO
Subset
None
Feedback
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Graph of GO:0005006

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Parents of epidermal growth factor-activated receptor activity (GO:0005006)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epidermal growth factor-activated receptor activity [is_a relation] is_a  transmembrane receptor protein tyrosine kinase activity (GO:0004714)
epidermal growth factor-activated receptor activity [BFO:0000050 relation] BFO:0000050  epidermal growth factor receptor signaling pathway (GO:0007173)
epidermal growth factor-activated receptor activity [BFO:0000051 relation] BFO:0000051  epidermal growth factor binding (GO:0048408)
Children of epidermal growth factor-activated receptor activity (GO:0005006)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) [RO:0002212 relation] RO:0002212  epidermal growth factor-activated receptor activity
positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) [RO:0002213 relation] RO:0002213  epidermal growth factor-activated receptor activity
regulation of epidermal growth factor-activated receptor activity (GO:0007176) [RO:0002211 relation] RO:0002211  epidermal growth factor-activated receptor activity
gurken-activated receptor activity (GO:0008313) [is_a relation] is_a  epidermal growth factor-activated receptor activity
None.