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Term Information

Accession
GO:0004888
Name
transmembrane signaling receptor activity
Ontology
molecular_function
Synonyms
transmembrane signalling receptor activity, transmembrane receptor activity
Alternate IDs
GO:0004926, GO:0099600
Definition
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. Source: Wikipedia:Transmembrane_receptor, GOC:go_curators
Comment
This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
History
See term history for GO:0004888 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Graph of GO:0004888

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Parents of transmembrane signaling receptor activity (GO:0004888)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transmembrane signaling receptor activity [is_a relation] is_a  signaling receptor activity (GO:0038023)
Children of transmembrane signaling receptor activity (GO:0004888)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
olfactory receptor activity (GO:0004984) [is_a relation] is_a  transmembrane signaling receptor activity
non-tyrosine kinase fibroblast growth factor receptor activity (GO:0001571) [is_a relation] is_a  transmembrane signaling receptor activity
acetylcholine receptor activity (GO:0015464) [is_a relation] is_a  transmembrane signaling receptor activity
G protein-coupled receptor activity (GO:0004930) [is_a relation] is_a  transmembrane signaling receptor activity
netrin receptor activity (GO:0005042) [is_a relation] is_a  transmembrane signaling receptor activity
apolipoprotein A-I receptor activity (GO:0034188) [is_a relation] is_a  transmembrane signaling receptor activity
opsonin receptor activity (GO:0001847) [is_a relation] is_a  transmembrane signaling receptor activity
neuregulin receptor activity (GO:0038131) [is_a relation] is_a  transmembrane signaling receptor activity
osmosensor activity (GO:0005034) [is_a relation] is_a  transmembrane signaling receptor activity
complement receptor activity (GO:0004875) [is_a relation] is_a  transmembrane signaling receptor activity
taste receptor activity (GO:0008527) [is_a relation] is_a  transmembrane signaling receptor activity
death receptor activity (GO:0005035) [is_a relation] is_a  transmembrane signaling receptor activity
reelin receptor activity (GO:0038025) [is_a relation] is_a  transmembrane signaling receptor activity
collagen receptor activity (GO:0038064) [is_a relation] is_a  transmembrane signaling receptor activity
latrotoxin receptor activity (GO:0016524) [is_a relation] is_a  transmembrane signaling receptor activity
ICAM-3 receptor activity (GO:0030369) [is_a relation] is_a  transmembrane signaling receptor activity
serotonin receptor activity (GO:0099589) [is_a relation] is_a  transmembrane signaling receptor activity
Wnt-activated receptor activity (GO:0042813) [is_a relation] is_a  transmembrane signaling receptor activity
glutamate receptor activity (GO:0008066) [is_a relation] is_a  transmembrane signaling receptor activity
hedgehog receptor activity (GO:0008158) [is_a relation] is_a  transmembrane signaling receptor activity
transmembrane receptor protein phosphatase activity (GO:0019198) [is_a relation] is_a  transmembrane signaling receptor activity
nucleotide receptor activity (GO:0016502) [is_a relation] is_a  transmembrane signaling receptor activity
cytokinin receptor activity (GO:0009884) [is_a relation] is_a  transmembrane signaling receptor activity
axon guidance receptor activity (GO:0008046) [is_a relation] is_a  transmembrane signaling receptor activity
neurotensin receptor activity, non-G protein-coupled (GO:0030379) [is_a relation] is_a  transmembrane signaling receptor activity
MHC class I receptor activity (GO:0032393) [is_a relation] is_a  transmembrane signaling receptor activity
semaphorin receptor activity (GO:0017154) [is_a relation] is_a  transmembrane signaling receptor activity
GABA receptor activity (GO:0016917) [is_a relation] is_a  transmembrane signaling receptor activity
cytokine receptor activity (GO:0004896) [is_a relation] is_a  transmembrane signaling receptor activity
sulfonylurea receptor activity (GO:0008281) [is_a relation] is_a  transmembrane signaling receptor activity
MHC class Ib receptor activity (GO:0032394) [is_a relation] is_a  transmembrane signaling receptor activity
immunoglobulin receptor activity (GO:0019763) [is_a relation] is_a  transmembrane signaling receptor activity
tiggrin receptor activity (GO:0005056) [is_a relation] is_a  transmembrane signaling receptor activity
MHC class II receptor activity (GO:0032395) [is_a relation] is_a  transmembrane signaling receptor activity
transmembrane receptor protein kinase activity (GO:0019199) [is_a relation] is_a  transmembrane signaling receptor activity
Reactome
R-HSA-193672