Planteome: Term Details for "MAP kinase kinase kinase activity" (GO:0004709)

Term Information

Accession: GO:0004709
Name: MAP kinase kinase kinase activity
Ontology: molecular_function
Synonyms: MAPK/ERK kinase kinase activity, MEKK activity, ATP:protein phosphotransferase (MAPKKKK-activated) activity, MAP3K, MAPKKK activity, MEK kinase activity, MEKK, MEKK1, MEKK2, MEKK3, MLTK, MLTKa, MLTKb, Mil/Raf, REKS, STK28, cMos, cRaf, mitogen-activated protein kinase kinase kinase activity, MLK-like mitogen-activated protein triple kinase activity
Alternate IDs: GO:0004710
Definition: Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. Source: PMID:9561267
Comment: None
History: See term history for GO:0004709 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to MAP kinase kinase kinase activity.; Link to all direct and indirect annotations to MAP kinase kinase kinase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for MAP kinase kinase kinase activity.
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0008150 biological_process
GO:0007154 cell communication
GO:0043170 macromolecule metabolic process
GO:0008152 metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0050896 response to stimulus
GO:0023052 signaling
GO:0065007 biological regulation
GO:0044237 cellular metabolic process
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006793 phosphorus metabolic process
GO:0048518 positive regulation of biological process
GO:0048522 positive regulation of cellular process
GO:0009893 positive regulation of metabolic process
GO:0019538 protein metabolic process
GO:0010646 regulation of cell communication
GO:0031323 regulation of cellular metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0048583 regulation of response to stimulus
GO:0023051 regulation of signaling
GO:0007165 signal transduction
GO:0003824 catalytic activity
GO:0044267 cellular protein metabolic process
BFO:0000001 entity
GO:0035556 intracellular signal transduction
GO:0071704 organic substance metabolic process
GO:0006796 phosphate-containing compound metabolic process
GO:0010647 positive regulation of cell communication
GO:0031325 positive regulation of cellular metabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0048584 positive regulation of response to stimulus
GO:0023056 positive regulation of signaling
GO:0065009 regulation of molecular function
GO:0051174 regulation of phosphorus metabolic process
GO:0051246 regulation of protein metabolic process
GO:0009966 regulation of signal transduction
GO:0006464 cellular protein modification process
GO:0000165 MAPK cascade
BFO:0000003 occurrent
GO:1901564 organonitrogen compound metabolic process
GO:0016310 phosphorylation
GO:0044093 positive regulation of molecular function
GO:0010562 positive regulation of phosphorus metabolic process
GO:0051247 positive regulation of protein metabolic process
GO:0009967 positive regulation of signal transduction
GO:0004674 protein serine/threonine kinase activity
GO:0050790 regulation of catalytic activity
GO:0032268 regulation of cellular protein metabolic process
GO:1902531 regulation of intracellular signal transduction
GO:0019220 regulation of phosphate metabolic process
GO:0045859 regulation of protein kinase activity
GO:0001932 regulation of protein phosphorylation
GO:0016740 transferase activity
GO:0044260 cellular macromolecule metabolic process
GO:0016301 kinase activity
GO:0043412 macromolecule modification
GO:0004707 MAP kinase activity
GO:0043085 positive regulation of catalytic activity
GO:0032270 positive regulation of cellular protein metabolic process
GO:1902533 positive regulation of intracellular signal transduction
GO:0045937 positive regulation of phosphate metabolic process
GO:0045860 positive regulation of protein kinase activity
GO:0001934 positive regulation of protein phosphorylation
BFO:0000015 process
GO:0006468 protein phosphorylation
GO:0043408 regulation of MAPK cascade
GO:0042325 regulation of phosphorylation
GO:0031399 regulation of protein modification process
GO:0071900 regulation of protein serine/threonine kinase activity
GO:0051338 regulation of transferase activity
GO:0005575 cellular_component
GO:0043410 positive regulation of MAPK cascade
GO:0042327 positive regulation of phosphorylation
GO:0031401 positive regulation of protein modification process
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0051347 positive regulation of transferase activity
GO:0004672 protein kinase activity
GO:0036211 protein modification process
GO:0043549 regulation of kinase activity
GO:0043405 regulation of MAP kinase activity
GO:0032147 activation of protein kinase activity
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0033674 positive regulation of kinase activity
GO:0043406 positive regulation of MAP kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0000187 activation of MAPK activity
GO:0140096 catalytic activity, acting on a protein
GO:0005622 intracellular anatomical structure
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004708 MAP kinase kinase activity
GO:0023014 signal transduction by protein phosphorylation
GO:0000186 activation of MAPKK activity
GO:0004709 MAP kinase kinase kinase activity
GO:0000185 activation of MAPKKK activity
GO:0051390 inactivation of MAPKKK activity
GO:0004706 JUN kinase kinase kinase activity

Parents of MAP kinase kinase kinase activity (GO:0004709)

subject	relation	object
MAP kinase kinase kinase activity	BFO:0000050	activation of MAPKK activity (GO:0000186)
MAP kinase kinase kinase activity	BFO:0000050	MAPK cascade (GO:0000165)
MAP kinase kinase kinase activity	is_a	protein serine/threonine kinase activity (GO:0004674)

Children of MAP kinase kinase kinase activity (GO:0004709)

subject	relation	object
JUN kinase kinase kinase activity (GO:0004706)	is_a	MAP kinase kinase kinase activity
inactivation of MAPKKK activity (GO:0051390)	RO:0002212	MAP kinase kinase kinase activity
activation of MAPKKK activity (GO:0000185)	RO:0002213	MAP kinase kinase kinase activity

EC: 2.7.11.25
MetaCyc: 2.7.11.25-RXN
Reactome: R-HSA-392530; R-HSA-450346; R-HSA-933530; R-HSA-450337; R-HSA-451649; R-HSA-168184; R-HSA-2730887; R-HSA-727819