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Term Information

Accession
GO:0004693
Name
cyclin-dependent protein serine/threonine kinase activity
Ontology
molecular_function
Synonyms
CDK activity, CDK, catalytic subunit activity, cyclin-dependent protein kinase, intrinsic catalyst activity, ATP:cyclin phosphotransferase activity, CDK, Cdk-activating protein kinase activity, cdk-activating kinase activity, D-type cyclin kinase activity, cdc2 kinase activity, cyclin D-cdk6 kinase activity, cyclin D-dependent kinase activity, cyclin E kinase activity, cyclin-A associated kinase activity, cyclin-dependent kinase 6 activity, cyclin-dependent kinase-2 activity, cyclin-dependent kinase-4 activity, neuronal cdc2-like kinase activity, cyclin-dependent kinase activity, cyclin-dependent protein kinase activity
Alternate IDs
GO:0016537
Definition
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK). Source: GOC:rn, PMID:7877684, GOC:pr, PMID:9841670
Comment
None
History
See term history for GO:0004693 at QuickGO
Subset
None
Feedback
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Graph of GO:0004693

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Parents of cyclin-dependent protein serine/threonine kinase activity (GO:0004693)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cyclin-dependent protein serine/threonine kinase activity [is_a relation] is_a  cyclin-dependent protein kinase activity (GO:0097472)
cyclin-dependent protein serine/threonine kinase activity [is_a relation] is_a  protein serine/threonine kinase activity (GO:0004674)
Children of cyclin-dependent protein serine/threonine kinase activity (GO:0004693)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736) [RO:0002212 relation] RO:0002212  cyclin-dependent protein serine/threonine kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737) [RO:0002213 relation] RO:0002213  cyclin-dependent protein serine/threonine kinase activity
regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079) [RO:0002211 relation] RO:0002211  cyclin-dependent protein serine/threonine kinase activity