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prostaglandin-endoperoxide synthase activity

Term Information

Accession
GO:0004666
Name
prostaglandin-endoperoxide synthase activity
Ontology
molecular_function
Synonyms
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity, (PG)H synthase activity, PG synthetase activity, fatty acid cyclooxygenase activity, prostaglandin G/H synthase activity, prostaglandin endoperoxide synthetase activity, prostaglandin synthase activity, prostaglandin synthetase activity
Alternate IDs
None
Definition
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. Source: EC:1.14.99.1
Comment
None
History
See term history for GO:0004666 at QuickGO
Subset
None
Feedback
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Graph of GO:0004666

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Parents of prostaglandin-endoperoxide synthase activity (GO:0004666)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prostaglandin-endoperoxide synthase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
Children of prostaglandin-endoperoxide synthase activity (GO:0004666)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of prostaglandin-endoperoxide synthase activity (GO:0060585) [RO:0002213 relation] RO:0002213  prostaglandin-endoperoxide synthase activity
regulation of prostaglandin-endoperoxide synthase activity (GO:0060584) [RO:0002211 relation] RO:0002211  prostaglandin-endoperoxide synthase activity