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Term Information

Accession
GO:0004660
Name
protein farnesyltransferase activity
Ontology
molecular_function
Synonyms
protein-cysteine farnesyltransferase activity, FTase activity, farnesyl-diphosphate:protein-cysteine farnesyltransferase activity, CAAX farnesyltransferase activity
Alternate IDs
GO:0018223
Definition
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. Source: EC:2.5.1.58, PMID:8621375
Comment
The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate.
History
See term history for GO:0004660 at QuickGO
Subset
None
Feedback
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Graph of GO:0004660

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Parents of protein farnesyltransferase activity (GO:0004660)
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protein farnesyltransferase activity [is_a relation] is_a  protein prenyltransferase activity (GO:0008318)

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