Planteome: Term Details for "calcidiol 1-monooxygenase activity" (GO:0004498)

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Term Information

Accession: GO:0004498
Name: calcidiol 1-monooxygenase activity
Ontology: molecular_function
Synonyms: 25-hydroxy vitamin D3 1-alpha-hydroxylase activity, 25-hydroxycholecalciferol 1-hydroxylase activity, calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating), 1-hydroxylase-25-hydroxyvitamin D3 activity, 25-OHD-1 alpha-hydroxylase activity, 25-hydroxy D3-1alpha-hydroxylase activity, 25-hydroxycholecalciferol 1-monooxygenase activity, 25-hydroxycholecalciferol 1alpha-hydroxylase activity, 25-hydroxycholecalciferol-1-hydroxylase activity, 25-hydroxyvitamin D-1 alpha hydroxylase activity, 25-hydroxyvitamin D3 1alpha-hydroxylase activity, cytochrome P450 CYP27B
Alternate IDs: None
Definition: Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+. Source: RHEA:20573, EC:1.14.15.18
Comment: None
History: See term history for GO:0004498 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to calcidiol 1-monooxygenase activity.; Link to all direct and indirect annotations to calcidiol 1-monooxygenase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for calcidiol 1-monooxygenase activity.
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GO:0008150 biological_process
BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0044281 small molecule metabolic process
GO:0044249 cellular biosynthetic process
GO:0006629 lipid metabolic process
GO:0003674 molecular_function
GO:1901360 organic cyclic compound metabolic process
GO:1901615 organic hydroxy compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044283 small molecule biosynthetic process
GO:0006766 vitamin metabolic process
GO:0006066 alcohol metabolic process
GO:0003824 catalytic activity
GO:0006775 fat-soluble vitamin metabolic process
GO:0008610 lipid biosynthetic process
GO:1901362 organic cyclic compound biosynthetic process
GO:1901617 organic hydroxy compound biosynthetic process
GO:0008202 steroid metabolic process
GO:0009110 vitamin biosynthetic process
GO:0046165 alcohol biosynthetic process
GO:0042362 fat-soluble vitamin biosynthetic process
GO:0016491 oxidoreductase activity
GO:0019751 polyol metabolic process
GO:1902652 secondary alcohol metabolic process
GO:0006694 steroid biosynthetic process
GO:0042359 vitamin D metabolic process
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0046173 polyol biosynthetic process
GO:0042368 vitamin D biosynthetic process
GO:0070640 vitamin D3 metabolic process
GO:0036378 calcitriol biosynthetic process from calciol
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0004498 calcidiol 1-monooxygenase activity
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity
GO:0060558 regulation of calcidiol 1-monooxygenase activity

Parents of calcidiol 1-monooxygenase activity (GO:0004498)

subject	relation	object
calcidiol 1-monooxygenase activity	BFO:0000050	calcitriol biosynthetic process from calciol (GO:0036378)
calcidiol 1-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

Children of calcidiol 1-monooxygenase activity (GO:0004498)

subject	relation	object
negative regulation of calcidiol 1-monooxygenase activity (GO:0010956)	RO:0002212	calcidiol 1-monooxygenase activity
positive regulation of calcidiol 1-monooxygenase activity (GO:0060559)	RO:0002213	calcidiol 1-monooxygenase activity
regulation of calcidiol 1-monooxygenase activity (GO:0060558)	RO:0002211	calcidiol 1-monooxygenase activity

EC: 1.14.15.18
KEGG_REACTION: R03610
MetaCyc: CALCIDIOL-1-MONOOXYGENASE-RXN
Reactome: R-HSA-209868; R-HSA-5602186
RHEA: 20573