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hydroxymethylglutaryl-CoA synthase activity

Term Information

Accession
GO:0004421
Name
hydroxymethylglutaryl-CoA synthase activity
Ontology
molecular_function
Synonyms
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity, 3-hydroxy-3-methylglutaryl CoA synthetase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthetase activity, 3-hydroxy-3-methylglutaryl-CoA synthase activity, 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity, HMG-CoA synthase activity, acetoacetyl coenzyme A transacetase activity, acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), beta-hydroxy-beta-methylglutaryl-CoA synthase activity, hydroxymethylglutaryl coenzyme A synthase activity, hydroxymethylglutaryl coenzyme A-condensing enzyme, hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity
Alternate IDs
None
Definition
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+. Source: RHEA:10188
Comment
Note that this function was formerly EC:4.1.3.5.
History
See term history for GO:0004421 at QuickGO
Subset
None
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Graph of GO:0004421

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Parents of hydroxymethylglutaryl-CoA synthase activity (GO:0004421)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hydroxymethylglutaryl-CoA synthase activity [is_a relation] is_a  acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)

This term has no children.