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dihydrofolate reductase activity

Term Information

Accession
GO:0004146
Name
dihydrofolate reductase activity
Ontology
molecular_function
Synonyms
dihydrofolate reduction, 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity, 7,8-dihydrofolate reductase activity, DHFR, NADPH-dihydrofolate reductase activity, dihydrofolate reductase:thymidylate synthase activity, dihydrofolic acid reductase activity, dihydrofolic reductase activity, folic acid reductase activity, folic reductase activity, pteridine reductase:dihydrofolate reductase activity, tetrahydrofolate dehydrogenase activity, thymidylate synthetase-dihydrofolate reductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. Source: EC:1.5.1.3
Comment
None
History
See term history for GO:0004146 at QuickGO
Subset
None
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Graph of GO:0004146

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Parents of dihydrofolate reductase activity (GO:0004146)
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dihydrofolate reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor (GO:0016646)

This term has no children.