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Term Information

Accession
GO:0003917
Name
DNA topoisomerase type I (single strand cut, ATP-independent) activity
Ontology
molecular_function
Synonyms
type I DNA topoisomerase activity, type I topoisomerase activity, nicking-closing enzyme activity, omega-protein activity, relaxing enzyme activity, swivelase activity, untwisting enzyme activity, DNA topoisomerase I activity, deoxyribonucleate topoisomerase, topoisomerase
Alternate IDs
None
Definition
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. Source: PMID:8811192
Comment
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
History
See term history for GO:0003917 at QuickGO
Subset
None
Feedback
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Graph of GO:0003917

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Parents of DNA topoisomerase type I (single strand cut, ATP-independent) activity (GO:0003917)
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DNA topoisomerase type I (single strand cut, ATP-independent) activity [is_a relation] is_a  DNA topoisomerase activity (GO:0003916)

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EC
5.6.2.1
MetaCyc
5.99.1.2-RXN