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Term Information

Accession
GO:0003878
Name
ATP citrate synthase activity
Ontology
molecular_function
Synonyms
ATP-citrate (pro-S)-lyase activity, ATP citrate (pro-S)-lyase activity, ATP-citrate (pro-S-)-lyase activity, ATP-citric lyase activity, ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity, ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating), acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating], acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity, acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating), adenosine triphosphate citrate lyase activity, citrate cleavage enzyme activity, citrate-ATP lyase activity, citric cleavage enzyme activity
Alternate IDs
GO:0046913
Definition
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA. Source: EC:2.3.3.8, RHEA:21160
Comment
Note that this function was formerly EC:4.1.3.8.
History
See term history for GO:0003878 at QuickGO
Subset
None
Feedback
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Graph of GO:0003878

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Parents of ATP citrate synthase activity (GO:0003878)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ATP citrate synthase activity [is_a relation] is_a  transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912)
Children of ATP citrate synthase activity (GO:0003878)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of ATP citrate synthase activity (GO:2000985) [RO:0002213 relation] RO:0002213  ATP citrate synthase activity
regulation of ATP citrate synthase activity (GO:2000983) [RO:0002211 relation] RO:0002211  ATP citrate synthase activity
negative regulation of ATP citrate synthase activity (GO:2000984) [RO:0002212 relation] RO:0002212  ATP citrate synthase activity
EC
2.3.3.8
KEGG_REACTION
R00352
MetaCyc
ATP-CITRATE-PRO-S--LYASE-RXN
PWY-5172
Reactome
R-HSA-75848
RHEA
21160