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Term Information

Accession
GO:0003713
Name
transcription coactivator activity
Ontology
molecular_function
Synonyms
transcription co-activator activity, transcription coactivator activity, RNA polymerase II transcription co-activator activity, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription mediator activity
Alternate IDs
GO:0001105
Definition
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator. Source: GOC:txnOH-2018, PMID:10213677, PMID:16858867
Comment
None
History
See term history for GO:0003713 at QuickGO
Subset
None
Feedback
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Graph of GO:0003713

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Parents of transcription coactivator activity (GO:0003713)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription coactivator activity [is_a relation] is_a  transcription coregulator activity (GO:0003712)
transcription coactivator activity [BFO:0000050 relation] BFO:0000050  positive regulation of nucleic acid-templated transcription (GO:1903508)
Children of transcription coactivator activity (GO:0003713)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear receptor transcription coactivator activity (GO:0030374) [is_a relation] is_a  transcription coactivator activity
None.