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Term Information

Accession
GO:0002927
Name
archaeosine-tRNA biosynthetic process
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs. Source: GOC:hjd, PMID:20129918
Comment
Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.
History
See term history for GO:0002927 at QuickGO
Subset
None
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Graph of GO:0002927

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Parents of archaeosine-tRNA biosynthetic process (GO:0002927)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
archaeosine-tRNA biosynthetic process [BFO:0000051 relation] BFO:0000051  archaeosine synthase activity (GO:0002948)
archaeosine-tRNA biosynthetic process [BFO:0000051 relation] BFO:0000051  7-cyano-7-deazaguanine tRNA-ribosyltransferase activity (GO:0043867)
archaeosine-tRNA biosynthetic process [is_a relation] is_a  tRNA modification (GO:0006400)
archaeosine-tRNA biosynthetic process [is_a relation] is_a  biosynthetic process (GO:0009058)

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