You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is at browser.planteome.org.

Term Information

Accession
GO:0002542
Name
Factor XII activation
Ontology
biological_process
Synonyms
Hageman factor activation
Alternate IDs
None
Definition
Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. Source: ISBN:0721601871, GOC:jal
Comment
None
History
See term history for GO:0002542 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
External term view.

Graph of GO:0002542

Viewing options
Parents of Factor XII activation (GO:0002542)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Factor XII activation [is_a relation] is_a  regulation of acute inflammatory response (GO:0002673)
Factor XII activation [BFO:0000050 relation] BFO:0000050  plasma kallikrein-kinin cascade (GO:0002353)
Factor XII activation [is_a relation] is_a  positive regulation of protein processing (GO:0010954)
Factor XII activation [RO:0002213 relation] RO:0002213  activation of plasma proteins involved in acute inflammatory response (GO:0002541)

This term has no children.

None.